Steer away from the head, as the snake may think that you are a predator. Mine are usually all balled up so I just pick them up wherever I think is the middle of them. Some people pick their snakes up by the tail end, I don't think that's a problem other than you really want to support them, I wouldn't like to be picked up by my toes... Be slow, firm and confident. Don't be afraid of them, and for heavens sake hold them well, you don't want to drop them. And naturally hold them with love and tenderness. I like to talk to mine while I pick them up in a comforting voice (I know they are deaf, but still, I like to think they can hear me maybe psychicly).