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Adventures in mouse breeding

Floof

New member
So, I recently decided to try mouse breeding again. Last time I tried it had its up's and down's, but overall was an interesting and actually kind of enjoyable experience (aside from the smell!).

Well, we're only a couple months in, and it's already quite interesting, again. Last time I tried mouse breeding, I started with 3 females: One who turned out to be infertile, one die-hard cannibal, and one who always had tiny litters (though, funny enough, her offspring went on to have perfectly normal litters!). This time around, once again, I've wound up with some... Interesting... females. Out of 6 girls, I have 2 or 3 who are perfectly normal, one who just took awhile to get preggers, and two who are totally weird.

To start, I have a small black female who is quite neurotic. Rather than use the wheel, she always runs in a counter-clockwise circle. NEVER clockwise, mind you! She's given me one litter so far, which counted in at 7 babies. There was an overcrowding issue, though, which I didn't realize was a problem until 2 pregnant moms started cannibalizing her babies, and in the end the count was 4.

Anyway, this strange little mouse was an equally strange mom. She would settle down and feed her babies... She was a good mom like that... But then she would pick up a baby, race in circles, and dump it on the other side of the tank. Wash, rinse, repeat with the other 3. I finally moved the litter into a different tank (those 2 pregnant moms, who gave birth just 1 and 2 days later). They fostered the little litter with no issues. All 4 are/were black selfs, just like mom. Now the other interesting part: Neurotic mom's female offspring just won't thrive! We wound up with a perfect 50/50 split. 2 males, 2 females, out of Neurotic Mom. The 2 males are fat, happy, and perfectly normal mice, right about weanling size right now. The 2 females... Well, one passed shortly after reaching the "hopper" stage. She was always the "runt," if you will, of the 3 litters. Even fully furred and having just opened her eyes, she was the size of a large pinky/small fuzzy. I tried moving her back into Neurotic Mom's tank, where one of NM's (not neurotic) cagemates had recently given birth. She didn't take, so, after a few days, she went back in with her original group. She passed a few days later. Now the second one is still alive and well... But, she, too, is smaller and overall weaker than any of the other 2 dozen, give or take, weanlings. I don't know if it's some strange coincidence, or what, but where NM's two male offspring are thriving and doing wonderfully, her two female offspring just aren't!

Considering the size we need most right now is adult mice, I suspect I'll have another couple chances to see whether NM continues to produce "runty" females and normal males, or if this little observation was a total fluke. It'll definitely be interesting to see what happens!

Now, the other strange Mom. Gold Mom was one of the original 2 females we picked up at a pet store up north. The employee reported that she'd been returned to the store the day before (or something like that) because the person who purchased her was upset that she wouldn't get pregnant... Or something. Anyway, she looked nice and pregnant to me, plus she's adorable, so I took her home despite. She plumped up, and, a week or two in, I could *swear* she was going to give birth the next day (and here's where I start hating myself for not keeping better records!). She continued looking like she'd swallowed a baseball for another week or more, before, one morning, I peeked in to discover a stillborn pinkie. Strange.. And she still looked preggers. Tossed the dead pink, and kept a close eye to see whether she would give birth to the rest of the litter over the next couple days.

Now, let's note here that these are feeder breeder mice. I'm not inclined to take a feeder breeder to a vet; rather, if something goes fatally wrong (so long as it's not dangerous to the snakes), that feeder breeder will quickly become snake chow. A sentiment I'm sure many here understand.

Gold Mom continued to look very pregnant, but not give birth, for another few weeks. Neurotic Mom gave birth, followed soon by the Agouti Girls. Another couple weeks later, Silver Mom also gave birth. But, still, Gold Mom continued to look very fat, very about-to-give-birth, and yet, day after day, not a single pinky was to be seen out of Gold Mom. Finally, earlier this week, Gold Mom gave birth! To a happy, healthy, beautiful litter of 10. Nothing dead, rotting, or otherwise what I was expecting from what appeared, for all intents and purposes, to be a month overdue litter. Nope, everything about her babies is perfectly normal. Everything about her is normal, too. Except, she STILL looks heavily pregnant. A little less heavily pregnant now that she's 10 pinkies lighter, but still very much with child. And there hasn't been a mature male in their tank since shortly after NM gave birth. What... The... Heck.

So, trying to imagine what in the world could be going on with her, my mind flashes back to an episode of Grey's Anatomy, in which one of their patients has 2 uteruses and, likewise, 2 pregnancies, conceived some weeks apart from each other. And my sleep-deprived brain wonders, is this possible in mice? I have no idea, but she sure is a weird mouse.

I actually think I'm going to give it a test eventually. Maybe leave her in with a male for a few weeks or whatever, and then move her in to an isolation tank to keep a closer eye on JUST her, keep super good records, and see what happens. Call it morbid curiosity, but I'm just completely fascinated by this girl.

In other news, we are up to 5 successful litters now (well... 4, depending on how you look at it!). Neurotic Mom's and Agouti Girls' litters are all about weaned, so we should be looking at 3 more litters here in the next week or so, and my male (because I'm "smart" and only have 1 male to 6 females in 3 different enclosures. Working on remedying that, though) is currently in with a very cute little Siamese gal (an "OMG must have!" from Petsmart) who is veeeery fat and due about a week after the Agouti Girls. Yes... I am currently drowning in baby mooses! But it's okay, because I have a very cozy freezer waiting for them, just as soon as they are big enough...

Aaaanyway, thank you for reading my middle of the night ramblings. Hope they were at least kind of interesting! It is now 2 AM... So I think I better actually try to sleep. (And perhaps in the future actually make an attempt at going to bed at a normal hour...) Anyone with thoughts on my two extremely strange gals, I'd love to hear it; everyone else, hope you enjoyed my rambling ooon and ooon, and good night! I'ma go pass out now. :)
 
If Gold Mom is a Dominant Lethal Yellow, that particular genotype is very prone to obesity - which would explain her extreme lightbulbyness.
 
Yeah, that would have been my first guess too. I've had female mice like that who are just fat due to constant eating (and genetics). I usually try to feed them off.
I've also had the random mouse here and there that would do as you described with the running in circles.
 
Ssthisto Lethal Yellow is not common in America(Mainly the show breeders have it over here), I bet she is an unmarked(no stripes) American Brindle (Avy) which is also prone to obesity. I have a few chuncky brindles :)
The black one either has/had and ear infection or some sort of brain injury. I had one girl that jump from my hands when she was a baby and she did the same counter clock wise spinning.
 
As others has mention, your gold mom is probably one of the breeds that is prone to obesity. The Black one just sounds like my ex-wife when we use to argue... round and round we went...lol

Is the male a fancy mouse too? The reason I ask is that I got a hold of a white mouse, from a breeder, that ended up being a different strain. Most of, but not all, his offspring tended to die after hitting the hopper stage, so of course he became snake food but not after spreading his weirdness into a few colonies(the few that did make it). Also the males tend to grow quicker than the females but it sounds like your males and female (from NM) are growing totally different. My black mice tend to be way more jumpy than the others but also tend to be the best mothers right next to my chubby brindles. :)
 
Cool, I wasn't even expecting to get any responses. Lol! Thanks for your thoughts, everyone!

Buzz, the male is a plain ol' REW. He's sired all of the litters so far (something like 40 or 50 babies, about 30 of which are at hopper or weanling stage), and so far Neurotic Mom's little litter is the only one with weird babies. Good to know about males usually growing faster! But, you're right--the girls out of NM are just growing different. There's... Crap, we counted them out and I can't remember. There's like 8 other females, I think it was, in that group who are all growing and thriving better than that one, too, and Silver Mom has 4 girls (in NM's tank) who are plump and happy, too, and just opened their eyes yesterday.

Is there such a thing as a genetic.. How would you put that... mental deficiency? That's only passed from mom to daughter? I've been planning to hold back one of her sons. It'll be interesting to see if whatever this is manifests in their litters, too, of if all their daughters turn out normal... Hmmm!

Regarding Gold Mom: I didn't even know mice had a lethal gene. :) I'll have to get a pic of her--"brindle" certainly does describe her well. Her base color is gold but she has greyish-brown markings down her back. I always figured it was just some kind of funky pattern, or something called "chimera" that I heard whispers of while browsing a feeder rat forum that, from what I gather, is about the equivalent of most paradoxes in snakes.

Now that you mention it, though, it's quite like my boxer, who is a relatively heavily marked brindle. It's actually kind of a relief that she's JUST fat! There's enough weird animals in this house as it is, lol. So what should I do about her? Should I worry about having her genetics in my colony, or does it matter? She's definitely a good mom--her babies are VERY well fed and healthy. I was hoping to hold back some girls from her either way because I looove the gold/brindle color; should I refrain, or only hold back females of a different phenotype?

Oh, and does anyone have ideas for a mousey weight loss program? Lol!
 
Wow! Mice are incredibly hard to photograph. Okay, so here's a pic of Gold Mom. I guess calling her "Gold Mom" is a bit confusing, considering she doesn't have a great deal of "gold" on her... Lol.
 

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I end up feeding off the ones that are prone to obesity just because if they remain obese, they generally stop producing all together (almost 100% of them for me).
 
Thanks for the link, Fishin. She's a sweet little mouse, but I'll probably go ahead and cull her. I'm sure it's stressful to only be able to run in a circle. What are your thoughts on keeping back one of her healthy-seeming males as a breeder? I haven't noticed any neurological behavior in them, but should I just not risk it? I would really like to have the black coloration in my colonies (watching genetics at work is half the fun! even if I don't know anything about mouse genetics, lol), but if it's too much of a risk I'll just find a healthy black mouse elsewhere. I'm just a bit loathe to have to do that because all the pet stores around here are awful, and mouse breeders seem to be pretty few and far between.

Tara--Thanks for the input. :) I'll be keeping an eye on her production rate, though it already seems low/slow compared to everyone else (one healthy litter in 2 or 3 months). I'm not thrilled at the idea of culling her if she's otherwise healthy, as she's a total sweetheart (for a mouse), but it's not out of the realm of possibility if she stops producing and/or nothing can be done for her weight.
 
Well from what i read about it when i had the female with the same problem, i do remember that it stated on some website,if its a brain disorder it can be passed on to the young.......My female only started showing signs of it around the 3 month stage, so i dont know how long it would take to diagnose any young with the same issues..........Sound like you have the breeding thing in hand, IMO, i would cull the young as well, just to be safe....
 
Thanks, Fishin. :) Good to know it can take so long to start presenting, too. I'll play it safe, then, and just cull both the males, too.
 
Gold mom is defintly an american brindle I have a few in my gang :)
Here is Tiger Lily, she is one of the best marked brindles I have ever had
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The main lethal gene to worry about in american is the varigated a form of dominant spot. If they get 2 varigate genes they are still born. Notice how jagged the edges are of her coat? Ressesive spotting, pied, has nice even lines and are usually more white.
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This girl was given 3 changes and she ate all 3 litters so she was fed off. I was planning on keeping just female varigated and cull all the males so I wouldn't have to worry about making the lethal combo.
If you didnt notice I'm a bit of a genetics nut lol!
 
Tiger Lily is stunning! And it's definitely so cool to know WHAT Gold Mom is. How does the American Brindle gene work? Gold Mom's babies are finally starting to get hair, and it looks like there's a few brindles in the mix. Dad is just a regular ol' REW.

And that's definitely good to know about the varigated spot. Thanks for the head's up! :)
 
American brindle is a dominant trait, so if she has one copy 50% will be brindles if she has 2 copies then 75% will be brindles. I love brindles I have had some pretty neat ones like snow brindles white with grey stripes. Some times the babies will be unmarked brindles and look yellow and some times they will be overmarked and look agouti.
I started breeding mice just over 5 years ago, the goal was to breed pet mice, but I ended up only finding buyers for snake food, not pets. So I learned the genetics and all that fun stuff!
 
That would sound about right--out of 9 babies (I thought there were 10-so I either miscounted, or someone died and was buried/eaten), it's looking like 3 brindles, 3 REW, and 3 agouti. I'm guessing REW probably masks Brindle? So there would be a possibility of one or two of the REWs carrying it?

The snow brindle sounds gorgeous! I just picked up a little group of spotteds. 2 spotted, 1 REW, and the fourth almost looks like some kind of reverse spotted, solid grey with small white spots. It looks like at least one of the gold mom's brindle babies is male, so I'm hoping to pair one of them with the spotted girls. I'm curious what a brindle spotted would look like. :)

I'm definitely going to have to sit down and start researching mouse genetics!
 
REW ruby eyed white is very rare in mice(one way to make one is yellow siamese, since the siamese gene wipes out the yellow colors), they are probley PEW's pink eyed whites.
The genes that make a PEW works just like bleach, it totally wipes out all pigment, in the fur and eyes. So the mouse can be genetically any color under the white, agouti, brindle, blue(grey) etc.
Here's 2 very fat brindles, one overmarked and one PEW
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Storm the snow tiger brindle he passed away a couple months ago.
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spotting gene is ressesive, so if your brindle boy carries it you might just get some :)
 
Ah, I didn't know that. :) I've always called them "red eyed white," or REW. Good to know, though--I didn't know there was a difference, lol!

Storm was gorgeous! And, wow, brindles sure can get huge...

Thanks for the head's up about spot being recessive--so I'll have to hold a male back to get my brindle spots (I highly doubt my brindles carry spot).
 
Love that tiger.. Wyld

This is a couple brindles of mine...I really need to learn more about the genetics. This has been a really neat thread, I learned quite a bit.



 
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