I had my mice in the plastic cages and two things happened within 24 hours that made me switch to aquariums:
the smell from them running on the wheel and peeing on it was so strong I couldn't leave it in the house without the smell greeting you as you walked in the front door and the mice were in the back office, it was that bad after one night.
Then my roommate's cat managed to pull the "extras" (all the pipes going to the wheel and lookouts) off and stick its paw inside. the extras would come right off on the two i had, it didn't take much effort at all. my mice chewed the cat up and it bled all over the place but wasn't able to pull them out. point for the cage... :grin01:
but (heres the kicker) when the cat left all the holes were open, the mice soon figured that out and escaped :bang:, we did eventually find all the mice, but I decided that an aquarium that has a locking lid and a wheel that i can pull out and hose down is much better for me. another plus is that with bedding covering everything the smell is not anywhere near as bad.