most are docile but hatchlings will be nervous at first. With handling, they may become very calm. Remember though, as with humans, corns are individuals and each has a separate, distinct personality. Some may be more calm and others may become irritated more easily. It all depends on the snake's personality. OF course, if it is mistreated or not handled for a long time, it may become leery of humans and become "wild."
Rarely do they bite unless of course the person's body part smells like mice. They rely on their sense of smell rather than sight.
Are you interested in getting a snake? If so, some people recommend for beginners to get a yearling or a juvenile rather than hatchlings because the older snakes have calmed down a bit and owners/breeders may have had a chance to observe the snake's personality and behavior.