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locus and allile

hediki

i luv them all.
i just wanted to know if in order to make a double het like a snow if botth alliles have to be able to connect on the same locus. i hope i didnt confuse any words :rolleyes:
 
Locus- Place that a given gene occupies on a chromosome

Allele- one of two alternate forms of a gene that can have the same locus on homologous chromosomes and are responsible for alternative traits; "some alleles are dominant over others.

To answer your question, anerythrism and amelanism are not on the same locus. If they were, I believe you'd get something very weird that looked half in between. I think that only thing this holds true for is for amel and ultra.
 
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Joejr14 said:
Locus- Place that a given gene occupies on a chromosome

Allele- one of two alternate forms of a gene that can have the same locus on homologous chromosomes and are responsible for alternative traits; "some alleles are dominant over others.

To answer your question, anerythrism and amelanism are not on the same locus. If they were, I believe you'd get something very weird that looked half in between. I think that only thing this holds true for is for amel and ultra.

A little fine-tuning:

Definition of locus is acceptable.

I'd change the definition of allele to "one of two OR MORE alternate forms...". Because if amelanistic and anerythristic mutants had the same allele, the wild type allele would make a third allele.

If two recessive mutant genes like the amelanistic mutant gene and the anerythristic mutant gene had the same locus, a heterozygous individual might look amelanistic, or it might look anerythristic, or it might look somewhere in between. All three possibilities have shown up at various loci in other species. The one thing our heterozygous individual would not look like is normal. Crossing amelanistic x anerythristic produces normal babies. This is good evidence that the two mutant genes are not allelic.
 
The key word is alternate.

One or two alternate forms of a gene (meaning one or two different from the wild type, no?).

This is where ulta and amel come into play. The both have the some loci.
 
The original post defined allele as "one of two alternate forms of a gene ... ". I took that to mean the wild type allele and a mutant allele.

The w locus in the fruit fly has over 100 mutant alleles in addition to the wild type allele. The definition must cover examples like that, too.
 
Okay well regardless of one, two, or many, the definition is still the same.

An alternative of the wild type gene that can have the same locus.
 
Certainly one part of the definition of "allele" must include that they occur at the same locus.

The latest wording makes it sound as if "allele" excludes the wild type version of a gene. So I had a look on dictionary.com. Here's the definition that I like best. "Any of the alternative forms of a gene that may occur at a given locus." (Source: Merriam-Webster's Medical Dictionary, © 2002 Merriam-Webster, Inc.) In this definition, there is no upper limit on the number of alleles, wild type is one of the "alternative forms", and all have the same locus.
 
I dont agree that 'wild type' or normal is included in the 'alternative form' of the gene.

If there's no normal form, what's there to be an alternative of? The very definition says that the wild type isn't included in the alternative grouping.
 
Alleles are variations that can be found at a particular locus.

This includes the wild type allele, and any mutant alleles. There is no inherent "THE gene for this locus." One alternative only happens to be called wild type because it's the one we think is most common.

For example, "the alleles that exist at the TYR locus are TYR, Amel, and Ultra." (TYR is the wild type.)
 
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