Putting Frontline spray (same ingredients as Frontline drops) on reptiles would be considered an off-label use, but you can call the toll free number on any package/bottle of Frontline and talk with someone at Merial. I'm not sure if you'll get the same response that I would, as I work for a vet, about off-label use. I know that Frontline has been used safely on alot of other mammals besides dogs and cats, but this is the first time I've heard it used on reptiles. Since the product is not absorbed into the system in mammals, I doubt it's absorbed in reptiles either, making it a very safe product.
Kimbyra - Sorry to hear about your kitty. You do need to be very careful with some products. Not all of the topical products act like that, however. Frontline and Advantage are the same products for both dogs and cats. The only difference is the amount used and perhaps the percentage/volume of the active ingredient in one of those products. K-9 Advantix, however, is very lethal if applied to cats. The ingredient added to Advantage to kill mites...permethrin, cannot be used on cats and the package has that fact marked all over it. That is, unless you perhaps purchased your product on-line and received product meant to be sold in another country. Labeling for another country can be different than for the U.S. as the requirements are different. In some cases, even the quality of the product may be different as well. Some on-line bargains really aren't bargains after all. There's usually a reason something is half the price than you would normally pay.