tyflier
[Insert Witty Commentary]
The size of your males is less important than the size of your females. I won't breed runt females, because breeding requires more from the female, and runts are likely to have smaller litters, overall. That is why I tend to holdback my largest female offspring.snakeboy24 said:thanks for the info. i will get another male mouse from a different shop. just as a point, my colony at the moment has a younger male mouse than the females. i think he is the runt. is it still possible for him to breed or if so would he be likley to have some deformed gienes? sorry if it sounds stupi but i a bit of a novice at gienes.
thanks
lee
While inbreeding may not be a huge thing to worry about, you need to try and account for the numbers of generations the mice have already been inbred for, as well as how many future colonies you would like to holdback from these mice. All things considered, I would rather invest $3 for a different male and thin out the bloodlines a little bit, than risk deformities or genetic problems from inbreeding. There really is no way of knowing how much inbreeding has already gone on in a colony, and anything I can do to prevent further inbreeding is going to help.
As Flagg said...lab mice are inbred for hundreds of generations. So are bulk rodent suppliers. This means that 90% of pet store mice are already inbred to a certain degree...a degree which is impossible to predict with any reasonable certainty. You could already be "on the verge" of genetic disasters and never know it. Why risk it when 1 male mouse can prevent it? For my money, $3 to thin out the blood line and gene pool is $3 well spent...