From what I can tell, the nightlife is somewhat limited to the small local bar scene in that area. Downtown Stuart has some very nice restaurants/bars you'll want to check out. Remember, you're so perfectly positioned there that you're only an short turnpike ride south to the West Palm, Ft. Lauderdale and Miami action.
When it comes to fishing...where do I start; anywhere you see water!!! Depending on what you are after, you've got the St. Lucie and Indian Rivers, inlets with jetty walls, beaches for surf fishing, bridges, piers, boat rentals and guides etc... Last summer I was surf fishing at Bathtub beach (you may have heard of it; if not, you will) and hooked more than 20 tarpon up to 200lbs.. I only landed one about 90lbs., but that was crazy stuff from the beach. Stuart is known for it's incredible snook fishing as well as being the sailfish capital of the world. I caught the biggest largemouth bass of my life out of the golf course pond directly behind my parent house (I own a bass boat and cover a lot water, I still catch more and bigger bass out of that silly little pond).
If you and/or your husband like to fish for something specific, let me know, I can put you in the right direction.