Well, it's true that i currently do not raise mice for my snakes, but I have bred mice in the past when I was a kid. Sometimes all you need is a male and female, but you are going to do a lot of work as well (cleaning cages, seperating/pairing mice, feeding, watering, etc). As for how often they breed, that depends on your individual mice and their health. Just keep in mind that a gestation period is about 18 days.