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Genetics calculator variation - a request......

paulh said:
In other words, the more loci are homozygous for the desired mutants, the better the odds of getting what you want.
Menhir said:
As said, breed two HypoLavenderBloodredStripes together and get the 100% odds.

Yes, that is the logical end of my statement. But my statement is true for any combination of homozygous and heterozgygous gene pairs. If even one parent is homozygous for the desired genotype at one locus, the odds of getting the desired results are better than the odds when both parents are heterozygous at all loci of concern. And inexperienced breeders have not had that fact pounded into them until it is second nature.
 
ecreipeoj said:
It seem as if I have seen photos you have posted of possible Lavender Caramels. Have you seen different results over the years in clutches that could have produced a Lavender Caramel? The reason I ask, is because of a question that was ask of Don S in a chat. Here is what he had to say about the combo many years ago. It seems as if yourself and others, may have had different results since this one.

Well at this point, I have two adult males who look like definitely positively maybe a combo of Lavender and Caramel, and I believe Hypo thrown in there as well, if I remember correctly. They did look slightly different as babies, but there were a lot of Hypo Lavenders thrown in the pot that were quite variable and were throwing the visual ability to discern everything off somewhat. Now after raising up a bunch, it does appear to be a definite visual marker for this combo. But as would be expected, those two adult males do not look identical either.

As for that clutch of Don's, I seem to recall that photo. But in hindsight, it just may have been that Don't luck was no better than mine tends to be. So he just did not get that combo wanted there.

ecreipeoj said:
Why do you think some Lavenders have normal eyes like your Avatar, and some have ruby eyes? Have you ever considered the possibility that “Mocha” and “Lavender” where alleles instead of the same gene? This is a very new concept, since we have discovered that Ultra is an allele with amel. This may answer some of the odd things we see in Lavenders such as our floating “hypo” like gene and the different results we see when combining Lavender and Caramel.

What if the breedings were actually, “Mocha” X Caramel, or “Lavender” X Caramel and the results were different? If they are alleles, we could see three different phenotypes in clutches when they are combined, which could be the answer to some of the odd results we see in the Lavender line, such as Don‘s “Hypos“, which I have seen in Lavender Lines that do not carry the Hypo gene. Is there just a “ruby eyed” gene or is it an indication of possible alleles?

Beats me. That red-eyed trait has been a chimera of sorts with me for a long time. You would think it would be something predictable in breeding trials, but I still don't have a clue as to what genetic parts are needed to make it appear upon calling. Certainly one would think that SOMETHING triggers it and it just doesn't appear when cosmic rays hit the animal at the right time during development or something.

The possibility of two lines of Lavender looking animals (Mocha and Lavender) are alleles instead of separate genes certainly could be a possibility, but it would pretty much have to be a case where an animal heterozygous for both Mocha and Lavender would have to look pretty much the same as either, or as an intermediary stage. Perhaps this is so, and that particular combo has been too subtle to notice all these years. So perhaps the red eye IS this combo? :shrugs: Possibly.... With nothing at hand to say what it IS, I certainly can't make any claims to say what it ISN'T. For that matter, it seems to me that the original Mochas mostly had ruby eyes from what I can recall, so maybe that black eyed form is the real indicator of something different? :shrugs:

ecreipeoj said:
I believe a breeding of a Hypo Lav Blood X Amber Blood would be the ticket. Hypo Bloods het Lav Car, would reduce the odds to 1 in 16 to produce a Hypo Lavender Caramel Blood.

Yeah, that may be on the roster for me in another year or so. Don't have an adult Amber Blood at the moment. I always tend to grow my animals up MUCH more slowly than any one else, I guess.
 
paulh said:
Yes, that is the logical end of my statement. But my statement is true for any combination of homozygous and heterozgygous gene pairs. [...] And inexperienced breeders have not had that fact pounded into them until it is second nature.

Maybe you got me wrong - of course you are right in that way. I was still thinking about your statement of an optimal/fastest way to produce XYZ and a reverse calculator would always find LavBlood X LavBlood to be the fastest way with the best odds to produce LavBlood. I was just thinking algorithmically and wanted to show, that such a reverse calculator would tell us many optimal solutions, that we do not need to know - at least not for the way we'd like to use it.
 
Austin M said:
I agree it would be great to have a reverse genetic calculator. Some thing else that would be cool is getting persentages or odds from poss. hets.
Example: Which would be the quickest path to get lav bloods stripe?

Would the odds be better to breed a lav blood X het blood stripe and deal with F1 bloods 50% poss het stripe

or breed a lav blood X stripe and deal with triple hets? This is just an example.

It would be very cool to have a program that would statistically show odds for poss hets to determine quickest breeding routes.

If I were aiming for Striped Lavender Blood (hey, I've just realised I've got the ingredients for that!) I would... well, I wouldn't start with the ones I've got here if I were aiming for Stripe Lav Bloods personally, because it'd be a long road - my pairs are 1.1 anery het glacier stripe, 1.0 coral snow poss het blood and 0.1 charcoal (+anery?) het blood. I'm mostly aiming at Lavender Anery Stripes and Granites right now :) With future plans aimed at getting lavender bloods in the third or fourth generation, whether or not they're striped.

I think, if it were going to be a long term project and I had money to burn, I'd want to start with the following (taken from Serpenco since that's the quickest photo/price list I can find):

1.0 Lavender Stripe X 0.2 Lavender Blood =

100% Lavender het blood, stripe.

Cross those (I'd keep 1.4 if I could) and you've got a 1-in-16 chance for your lavender blood stripes in the second generation. Having four females increases the chances of a visual quite a bit, too.
 
Menhir said:
Maybe you got me wrong - of course you are right in that way. I was still thinking about your statement of an optimal/fastest way to produce XYZ and a reverse calculator would always find LavBlood X LavBlood to be the fastest way with the best odds to produce LavBlood. I was just thinking algorithmically and wanted to show, that such a reverse calculator would tell us many optimal solutions, that we do not need to know - at least not for the way we'd like to use it.
Yes, I think I did misunderstand. I agree 100% with this post.

So people do not want the optimal solution because it does not exist (yet). They want the best available suboptimal solution. Without a database of available stock to choose from, a reverse genetics program could only give all possible ways to arrive at the desired outcome in one generation. And the program might give the odds for getting what is wanted from a given mating.

So the problem boils down to how to present all the possible matings without swamping the user with indigestible information. One way is to break one big problem down into several small problems, by examining one locus at a time. That's what I did in an earlier post in this thread.
 
As soon as there is a genetical database of ones stock, the reverse calculator would be no problem. I think I would have to use Java or something like that instead of a web solution with PHP like my currect calculator. But I think it wouldn't be hard - just hard to find time while doing a PhD and caring for my animals.
 
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