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Cryptosporidium/ regurg and vomiting

charlie1

New member
This has kind of been on my mind since I learned of it. I cant find any reference to how snakes get this parasite so if anyone has more info I would like to know. That being said I suspect tainted mice/rats and lizards.

Further down in the forum below is a very good post about the difference between regurgitation and vomiting that I though some might find interesting and how it can be used to determine whether crypto is an issue. here is what the post says:

"It is important also to make the distinction between regurgitating and vomiting. Regurgitation is bringing the food item back up from the stomach and usually occurs within 24 hours of feeding. Vomiting is bringing the food item back up from the intestines and occurs after about 24 hours of feeding. Vomited food items will appear partially digested and will have a strong odor. Whether the snake is vomiting or regurgitating can help determine what the problem is....OK. If they are vomiting, it's not likely Crypto. I would be more inclined to go along with temperatures as a likely culprit, or possibly intestinal parasites".

Here is the link:

http://www.faunaclassifieds.com/forums/showthread.php?t=59694
 
I would also like to know how they get Crypto. I can't find info about how common it is in wild snakes, or how much of a risk it would be to have a wc snake anywhere near a cb one.
 
I don’t think I agree with that distinction between vomiting and regurgitation. Regurgitation is used to describe bringing food back up usually voluntarily. Many birds do this to feed their young. Owls regurgitate pellets of indigestible matter like bones and fur. Snakes will regurgitate voluntarily if the have a full stomach and feel threatened or if their stomach is full of something they cannot digest for some reason. Vomiting is more along the lines of what humans do when they are ill and vomit involuntarily.

Crypto is a parasite that live in the intestines. The eggs or oocysts are passed with the feces of the animal. In order for it to spread to another animal the oocysts have to be eaten by a prey animal and then the prey animal is eaten by another reptile. This is very common in lizards. The insects they eat often feed on their feces. Especially in captivity. If your cages are not cleaned and you throw in a bunch of crickets they could very easily pick up the oocysts.

Crypto is not a common thing. You are a breeder will likely go your entire life and never see it. It is not something you need to watch for or be aware of. If your snake regurgitates it is most likely from many different causes that are not crypto. That would be one of the last things I would start to worry about.

If you are feeding frozen mice and none of your reptiles have crypto now the odds are extremely low that you will ever see it.

Wild caught snakes are always a concern. You are more likely to bring mites and ticks into the collection. To prevent contamination to your other snakes a WC snake should be quarantined carefully for 2 or 3 months before you bring it into your snake room. Never play musical mice. If you snake does not eat, flush the mouse. Never offer it to another snake.
 
Have to say I agree with Wade - that all sounds a bit questionable.

If you accept the different definitions of "vomiting" and "regurgitating" (which I don't), then the author is effectively saying that any snake that regurgitates within 24 hours of eating, probably has Crypto.

That's plainly wrong, otherwise the bulk of us would have collections riddled with Crypto. Very few people who've kept Corns for any length of time, have NEVER experienced a regurge. Can't remember the last time I saw it - it's certainly been a few years - but I've definitely had a handful in the 19 years I've owned them.

There are many, far more work-a-way and boring, causes of regurgitation within 24 hours of eating. Off the top of my head, I can think of:
- Incorrect husbandry (too hot/too cold)
- Inappropriate handling
- Stress (being moved, cohabiting, not enough hides)
- Eating too near a shed
- Eating a larger food item too soon, when moving up to a new food size (this is factor that's caused the ones in my collection, as far as I can tell)

I think the author of the quoted guidelines is being over-dramatic.
 
Crypto is not fully understood and is probably more common than most herpers realize. As a coccidia, transmission can be through water, direct contact with contaminated surfaces/objects, intermediate hosts and transmitted through the use of vectors such as flies. They haven't figured out everything about dog, cat and human coccidia yet so reptile coccidia sure isn't high priority. In many cases, the coccidia is present but does not cause illness. It is only a problem when it's in an individual with a lower immune system, or is stressed, or some unknown factor that it can cause a problem. I'll bet that more than 75% of all corn snakes have a small number of crypto oocysts in their system and live normal healthy lives.
 
Crypto is not fully understood and is probably more common than most herpers realize... I'll bet that more than 75% of all corn snakes have a small number of crypto oocysts in their system and live normal healthy lives.
Really? I didn't think it was that prevalent that does give one cause to think. I'm pretty sure you would know more than I working for a vet's office. So, if 75 percent of all snakes really were carriers, that would mean a majority of collections have crypto unknown to the owner because they appear healthy. Who is going to go pay a vet for fecals to be done when the snake is doing fine.
Yet when people find out there is crypto in their collection the snakes are often all destroyed and other such drastic measures. I wonder, if crypto is so common, is this too drastic of a measure to be taking? If a snake can be exposed to it and appear perfectly healthy is it necessary to euthanize it to prevent the spread of crypto as some people have done because of another snake in their collection getting sick? Just makes me wonder.
I do think most regurges are for the reasons Bitsy gave though - temps, food size, shed cycle, etc.
 
Susan, could you comment on the difference between regurgitation and vomiting? What is your definition?
 
I have had a couple of people ask me about crypto in the last few days. It’s been a long time since I have read about it so I got the books back out this morning. Here is what I have learned.

First there is not a lot understood about it. In general Coccidia is a common protozoan that is acquired by exposure to fecal material through food, water or environment. It is much more common in captive reptiles because captive reptiles are more likely to encounter fresh fecal material than are wild snakes. It has not been proven nor disproven if the reptilian parasite can be transferred to mammals. Some believe it can be. One suggested source is if wild mice come in contact with your domestic mice and pass the oocysts through their feces to your mice. The most likely way to transmit it through your collection would be through sharing of water bowls or musical mice or on your hands as you handle different snakes.

Most commonly snakes that are immunocompromised are at risk, this would include young snakes or very stressed snakes. Healthy snakes my not show any symptoms or they may have mild diarrhea for 2 to 4 weeks. Healthy snakes can however be carriers and pass oocysts for up to a year.

The symptoms for lizards are different than for snakes. I am only talking about snakes here. The parasite causes extreme irritation of the stomach walls causing them to thicken. This leads to regurgitation. A firm mid body swelling may be one of the symptoms but this does not always show. Death is the likely consequence although they may linger for years.

Reasons to suspect the presence of cryptosporidia in snakes:

Failure to respond to conventional therapy
Extreme weight loss (60-70%)
Depression
Mucus-laden, cottage-cheesy stools
Mid-body firm mass.

Cryptosporidosis is thought to have no treatment.


WOW check out some of the big words I just used. Most of that I have paraphrased from a book by Roger J Klingenberg D.V.M., “Understanding Reptile Parasites”. Hope that answered some questions.
 
Failure to respond to conventional therapy
Extreme weight loss (60-70%)
Depression
Mucus-laden, cottage-cheesy stools
Mid-body firm mass.

This made me LOL. How can you tell if your snake is depressed?

Common signs and symptoms of depression:

Feelings of helplessness and hopelessness.
Loss of interest in daily activities.
Sleep changes.
Irritability or restlessness.
Loss of energy.
Self-loathing.
Concentration problems.
Unexplained aches and pains.

LOL I think my snakes is self loathing..

Heehee, just giving you crap Wade. Good post though, this is something I wasn't even aware of and Now something I will have to read up on. Since I rotate my snakes through a feeding bin and I DO sometimes give another snake an unwanted mouse when I move that other snake into the bin. I do wipe my bins out but don't sanitize them between snakes... What are your thoughts on that? Should I sanitize the bins in between feedings then? To me it would be similar to the musical mouse dealio, since the mouse was virtually untouched by the snake that didn't want it but yet, that snake was sitting in that bin (Of course quarantined snakes have a separate bin).

Note: hopefully this has not posted multiple times. My work is currently attempting to block this sight with something called Websense, sometimes I can view and sometimes I cannot, sometimes I can post and sometimes I cannot.
 
I don't play musical mice. I probably would not worry about the feeding bin unless I had some reason to think I had crypto. You can't spread it unless one of your snakes has it. I don't know how paranoid you want to be.
 
Really? I didn't think it was that prevalent that does give one cause to think. I'm pretty sure you would know more than I working for a vet's office. So, if 75 percent of all snakes really were carriers, that would mean a majority of collections have crypto unknown to the owner because they appear healthy. Who is going to go pay a vet for fecals to be done when the snake is doing fine.
Yet when people find out there is crypto in their collection the snakes are often all destroyed and other such drastic measures. I wonder, if crypto is so common, is this too drastic of a measure to be taking? If a snake can be exposed to it and appear perfectly healthy is it necessary to euthanize it to prevent the spread of crypto as some people have done because of another snake in their collection getting sick? Just makes me wonder.
I do think most regurges are for the reasons Bitsy gave though - temps, food size, shed cycle, etc.

My numbers are not based on actual testing in snakes, just a possibility based upon what I see in a percentage of fecal exams I perform on dogs and cats where I find other coccidia species, plus things I have read and/or heard at the vet conferences I've attended over the years. As mentioned by Wade in his search of info, coccidial protozoans are more of an issue in already compromised individuals. We see more coccidia oocycts in fecal samples from puppies and kittens than in adult pets, and they are present in a much higher percentage in samples that also contain another parasite ova or in those that are from pets that are ill in one way or another.

Florida law requires that all puppies and kittens sold must be free of internal parasites. Eliminating coccidia completely in fecal samples of some litters is so difficult that making sure that the sample reads negative on the exact day the health certificates are issued has become almost an art form. Everyone knows that the puppies or kittens are in perfect health and that the odd coccidia oocyst means absolutely nothing, but should something happen in the future, we can swear in a court of law that the sample we read was negative. Some breeders seem to have more of a problem than others, but that also seems to fluctuate based upon the time of year, the number of litters they have on the ground at one time and will be a problem with one breeder this year, and not the next and then turn up in a breeder that has never had a problem before.

So based on that, I would dare say that if someone were to sample every snake in their collection tomorrow, they would find some that show a few oocysts. Now prove what species of coccidia it is, and then determine if it is actually causing a problem or not. Can cryptosporidosis be a major health concern, causing fatalities and spreading throughout a collection? Of course! But does someone have to destroy his entire collection because one snake regurged and on the third fecal sample tested, a coccidia oocyst was present, maybe not. If someone has a snake that has been regurging, has lost dramatic weight and shows the mid-body firm mass, and then tests positive for oocycts (and I mean hundreds of oocysts for any animal that is symptomatic), I would say there is a big problem and they need to quarantine and euthanize any snakes that show symptoms to prevent a wide-spread outbreak in their collection. But any snake in that collection that remains healthy, never regurgitates, maintains weight, etc and stays that way for years, I really don't think it needs to be euthanized, even if in one sample taken 16 months after the initial diagnosis, a few oocycts are seen.

Do some people go "overboard"? Good question. Maybe "yes", maybe "no". It all depends upon your own personal take on things. I work with a woman who was completely germophobic when she started. She would spray Lysol on everything someone else touched, would refuse to pick up anything that fell on the floor, and literally "hosed down" a co-worker with Lysol after that co-worker coughed due to the common cold. And yet, she had no issue handling money, one of the filthiest things around. For her first couple of years working at the clinic, she got sick (colds, simple stomach bugs, etc) quite frequently. Over the years, when she had to stop with the Lysol or get fired, she became less phobic, got exposed to the run-of-the-mill germs she had been so afraid of, and low-and-behold, built up a natural resistance to them and now rarely ever gets sick! Keep yourself, or your snake, in a glass bubble and the body forgets how to fight for itself against the simple little every day germs.

Susan, could you comment on the difference between regurgitation and vomiting? What is your definition?

To me, regurgitation is more of a voluntary action used to provide food for the young or your mate. Vomiting is an action to empty the stomach for any other reason, no matter how long the contents have been there. The terms are synonyms for each other and medically, there are many different kinds of vomiting, from projectile to dry to cyclic, etc. The corn snake community, or maybe the herp community as a whole, has gotten "regurge" stuck in their terminology, probably because when it happens in snakes, they see the partially digested food item still "whole", and when they think of "vomit", they think of the chewed up, more liquified, partially digested stomach contents they themselves have left in the porcelain bowl. "Barf", "up-chuck", "hurl", "puke", et al are other synonyms, but they even sound worse than "vomit". "Regurge" is much nicer, but I'm going to maybe start to use "emesis" more frequently. In any case, you can :puke01: or you can :puke02:, it all comes out the same in the end.
 
Mouse Parvo will throw a false positive in a fecal test of a Snake as well.. Leopard Gecko's are norotious for carrying their form of crypto, and it is thought that greater percentage of leo's out there will test positive for their form of crypto.. There are many, many different strains of crypto/parvo out there..

Husbandtry is a big factor.. Keep it clean...
 
So can someone knowledgable comment on preventing the spread of crypto if there is a snake in a collection that is symptomatic/questionable, or if you have a new snake? Does antibacterial soap get it off your hands? Hand sanitizer? Bleach solution? How long can it live in the environment and pose a threat to infecting a healthy snake? Even a decent reptile disease/parasite website/book referral would be appreciated as I'm interested in learning more about this problem and others. Thanks.
 
Sorry one more question re: crypto. Is regurgitation generally the first sign or even a universal sign? And how quick is the progression in a symptomatic snake? Would you expect it to lose weight VERY quickly and succumb w/o any treatment, or is the course of the disease slower? If snakes can be carriers/asymptomatic, why isn't the parasite more widespread? (or maybe it is, as Susan said above). Do all snakes get crypto, or just certain species?
 
Here is a small article on Crypto I wrote up based on research done in 2007. I worked for a medical journal printer and we did an Exotics Veterinarian one that had all the latest studies in (pretty cool stuff). Their is also a discussion somewhere here on Cornsnakes.com that contains quotes from the study and scans of the charts (outlining the different strains found in reptiles).

Erika, here is the answer to your first question...

Crypto oocysts are only neutralized by exposure to moist heat between 113°F and 140°F for 5 to 9 minutes and by disinfection with ammonia (5%) or formal saline (10%) for 18 hours. Ineffective disinfectants included idophores (1%-4%), cresylic acid (2.5% and 5%), sodium hypochlorite (3%), benzalkonium chloride (5% and 10%), and sodium hydroxide (0.02 m). Anything that could have potentially been in contact with an infected reptile should be thoroughly cleaned with an ammonia solution and allowed to dry for a period of at least 3 days.

Information may have changed in the last three years, but I find it unlikely. Reptile Crypto isn't high on the funding food chain.
 
Sorry one more question re: crypto. Is regurgitation generally the first sign or even a universal sign? And how quick is the progression in a symptomatic snake? Would you expect it to lose weight VERY quickly and succumb w/o any treatment, or is the course of the disease slower? If snakes can be carriers/asymptomatic, why isn't the parasite more widespread? (or maybe it is, as Susan said above). Do all snakes get crypto, or just certain species?

From what I've heard/read, regurgitation is a common symptom and often the first one recognized, but the other signs, or none at all prior to sudden death, can also be seen. I'm not sure if all snake species are susceptible, but I would say they are, but there may also be varying degrees of susceptibility between the species. I'm really not sure how well studied that part is, and the answer possibly correlates to how common the different species are and how well studied each species is.
 
cobained, something I would like to point out is first off, Susan is very smart and you should listen to her.

Secondly, keep in mind that crypto is not really common in snakes and there are many causes of regurgitation that do not involve crypto. If one of my snakes were to regurgitate, I would spend a month looking at other causes before I would start to think about crypto.

The crypto parasite lives in the stomach of the snake and the eggs are passed out with the feces. The parasite is spread by allowing other snakes to come in contact with that feces or by mice that have come in contact with the oocysts. Mice can carry the parasite too but it is not clear if it is the same species that infects reptiles.

The real question is not how to kill the oocysts. You can remove it from you hands with a good washing. Antibacterial soap will not kill it but you can mechanically remove it by washing. Many of the solutions the TME listed above may kill the parasite but would also kill your snake so caution should be exercised if you are using any of them.
 
Many of the solutions the TME listed above may kill the parasite but would also kill your snake so caution should be exercised if you are using any of them.

My apologies for the confusion...What I posted on what is successful at killing Crypto was merely presented as a scientific standpoint and should not be used on an animal. Scientifically those are the methods the experts have found are successful on eradicating the actual parasite. The most you can do with that information is clean things that came in contact with an infected animal.

The symptoms can be treated, but their is no cure for crypto.
 
Thank you for the information. As a research tech at a university, I enjoy the scientific aspect as well as the husbandry side of disease, and I have come to be much more skeptical of claims made with no scientific basis and by people I generally don't know. I certainly respect the opinions of the people on this forum, which is why I read it so frequently, but have also seen opinions posted by people who maybe are new or simply not knowledgable enough to provide a trustworthy response. I did read Susan's posts, and I appreciate her taking the time to provide the information. I just have a difficult time understanding one person saying possibly 75% of snakes carry the parasite, and someone else saying it's super rare.

And to be even more honest, my recent interest in Crypto is due to an issue I'm having with one of my own hatchlings. She's an 09 I bought out of the egg from a breeder on here along with about 5 other hatchlings. I've had her since October and she's been perfect. She recently developed a swollen belly with no other symptoms, and though the vet she's seeing does NOT suspect crypto at this point and is treating her for other parasites, I can't help but wonder and dread if it is. You can imagine how stressful that is for someone who understands the ramifications of that, for that snake and for the rest of my collection.
 
It's rare that an individual admits to having Crypto as it can be a death sentence for a business due to it being highly contagious and having no known cure...That doesn't mean that the parasite itself is rare. I agree with Susan (and their are studies that support it) that Crypto is a lot more common the most think. Carriers can go their entire life without symptoms but still spread the parasite.
 
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