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I'm having a major problem with my girl...NEED HELP!..

medusacoils

Mr. Enigma!
A few years ago, I purchased my girl Oracle. Beautiful Striped Snow that I had big plans for.

It all started this winter and has progressively gotten worse. It started off that she began losing weight. Even though she was eating well. She is five years old and weighed in at close to 400+ grams. Has, and still has, a ferocious appetite.

Earlier this winter she began losing weight. Very subtle weight loss. She was still eating good, but not doing good. Then she began to regurge, which is a really big concern for me. So I took her to the vet. The vet I use I have a lot of confidence in. They exclusively see, and if necessary, treat all the reptiles that NERD's (New England Reptile Distributors) and they have a lot.

The first thing they did is check her stool for parasites. That came back negative. They also treated her for a bacterial/uri, not because she had one, but because it was a potential. She clicks when she breaths. She still clicks when she breaths, but they think its just the way she breaths. Her mouth and nostrils are void of mucous. They also checked her trachea and that was clear.

After all this, I decided to take her home and just work with the treatment for a while and see how things go. She was on Baytril orally, twice daily. I held back on food while going to through the treatment. I also raised the temps in her viv to 90F on the warm side and 80F on the cool. After the course was completed, I began a post regurge protocol. She seemed to respond to that well, for a while anyway.

Then she began to regurge again. Also, I noticed that her belly was a bit distended. I called the vet again and we decided that we should check her for cryptosporidium. They performed a gastric lavage on her. The vet told me that they were able to get a good sample from her and sent it off for testing. Fortunately that came back negative for crypto. The vet checked her belly and the swelling is at her stomach and it is air. He took a few x-rays of her just too see and all of those were clear.

He wanted me to just go home and continue with the post regurge protocol and see how that goes. If I have anymore problems then to call or come back. Things, again, went well for a little while. A month later she regurged again. I also checked her weight and she lost close to 140grams. I called the vet again. He had me bring her back. He did a cloacal swab on her and took a blood sample. He also wanted to keep her for a while because she was dehydrated. I went home without her.

To my relief all of those came back negative. They checked her liver, kidneys and for any other types of infection. They had to give her some fluids intravenously and she was good. They kept her for four days. He has no idea what is wrong with this snake. Then Oracle came home again.

Things didn't improve this time. She was still having issues with weight and she would regurge even with smallest meal. I wasn't feeding her anything bigger than a pinkies head and I was waiting long periods between feedings. I decided to go for a second opinion. I got her record from the previous vet and contacted another vet who specializes in exotics.

She read through all the notes and examined her. She also re-weighed her. Now she was pushing around 220grams. She tried to take a swab of her cloaca, but there wasn't any fecal matter. We then decided to go with another gastric lavage and blood test. Those were both performed and came back negative. She also took several x-rays of her in an attempt to see if there was something going on. Those were negative. So now she has no idea what is wrong with her. Blames on failure to thrive which is something I think they are saying just because they don't know.

I'm asking for your(CS.com community) help. Maybe you can think of something that we haven't thought of yet. Maybe you had an experience with this and can give me advice.

Just to give you a break down on what has happened.

  1. I have checked and double checked her husbandry. Her temps are perfect.
  2. She is sequestered from the other snakes in my collection.
  3. She has had three fecals (both swab and actual) done. All Negative.
  4. She has had two sets of blood test done. Both Negative.
  5. She has had two gastric lavage's done. Both Negative.
  6. I don't feed her anything bigger than a pinkie.
  7. She has lost close to 200grams at this point.
  8. She has a distended belly that is from air and is not solid.
  9. She has spent 4-5 overnights at the vet.
  10. She regurges often.
  11. She dehydrates easily.

I bought the snake for around $200. I have spent over $1200 on her and I will spend more if I can make her better. I just don't want her to suffer. She is fairly active for a sick snake.

Here are a few pictures of her so you can see her when she was healthy.

OracleKnot.jpg

Oracle4.jpg
 
The gas in her belly as well as regurgitation makes me wonder about a partial bowel obstruction.

When you did the gastric lavages, had she had a meal at around that time, so if she _did_ have crypto, it would have been "shedding?" Two negatives, though, seems encouraging.

When you say her belly is distended, you mean her belly in general, not a thickening of the walls of her stomach from inflammation? So a more non-specific area?
 
Maybe nanci could help with this, but have they seen anything in her intestine when they did the x-rays? Any eggs? Inneseception or slug soup or something weird preventing food from moving through her body? I dunno sir.

Please keep us updated. Are they sure her stomach digesting acids are being released? Does she regurge water?
 
The gas in her belly as well as regurgitation makes me wonder about a partial bowel obstruction.

When she does eat and keep it down, she poops fine. That was one of the things the vet looked for when he did the x-ray.

When you did the gastric lavages, had she had a meal at around that time, so if she _did_ have crypto, it would have been "shedding?" Two negatives, though, seems encouraging.

I cannot remember, but what I do remember with the first one is that I was asked that question and when I gave my answer, the doc wanted to do the test. He did say that the timing was good. The second vet told me that by having two negatives that I should rest that crypto isn't the culprit here.

When you say her belly is distended, you mean her belly in general, not a thickening of the walls of her stomach from inflammation? So a more non-specific area?

It's air in her belly that is causing a slight swelling. With massage the air will expel and the belly will turn normal again.




Maybe nanci could help with this, but have they seen anything in her intestine when they did the x-rays? Any eggs? Inneseception or slug soup or something weird preventing food from moving through her body? I dunno sir.

Please keep us updated. Are they sure her stomach digesting acids are being released? Does she regurge water?

No eggs or bowel obstructions noted. She doesn't regurge water. Just partially digested pinkie or pinkie parts. Her regurging isn't constant. It's every 3rd meal or so. Then she will regurge 3 meals then eat 3 or so fine.

Last week was the first regurge in about a month. It occured about 24 hours after she was fed and the majority of the large pinkie was digested. It stunk bad. I actually sent that mouse to the vet for testing. I was supposed to get a call back yesterday, but didn't. I should hear about it Monday.

________


I really appreciate the help and concern on this matter. I'm very concerned for this girlie and I'm holding vigil that she will be fine. If I don't begin to see a turn around soon, I may have to consider the unthinkable. I don't want to rush to judgement on this so I am giving it more time.

I just don't want her to suffer.

Wayne
 
I don't know enough about illnesses in snakes to be any help, but know that I'm thinking about you both, and wishing for the best!
 
Wayne, I have been thinking and thinking about this and keep coming up empty. I am so sorry you and Oracle are going through this.
Crypto is the only thing I can think of...and it's not that.
Is cancer a possibility?
 
I too have come up with nothing. I am sorry for your troubles. but if you have already taken the snake to the vet and they have tested it for everything you could suspect it is hard for anybody else to say what it is. Very frustrating, all I can think of is that if you can get her to recover from the regurge with feeding protocols again you will probably just have to keep her on real small food items more often. I'm assuming you have already tried nutribac here. I'd also suggest trying the grapefruit seed extract (a couple of drops in the water every time you change out the bowl) it might not help but it won't hurt, an old remedy I used to see suggested a lot for regurges and not so much anymore.
 
Could she be lacking some kind of digestive enzyme? I really know close to nothing about snake illness, but I had read about a cat a couple months ago who was having constant gastrointestinal problems. The owner tried everything, had all sorts of tests done, tried dozens of different foods - the other cats were fine, just 1 particular cat was having problems. She ended up getting some kind of digestive enzyme drops and putting them in the food every day resolved the cat's problem. Maybe she just makes such small quantities of the substance, she can only digest the occasional tiny meal? I don't know if the tests you had look for that kind of thing?

Sorry I can't be more help, I really hope she starts getting better. :(!!
 
Did you already add Nutribac to her food items? It might just help her a bit.

Has she been tested for Chlamydophila psittaci (colorign test)? It's not a standard test with snakes, since it's not really known snakes can get infected with it. I have had a break out of that in my collection, and though the symptoms were not the same, you might just want to eliminate the option. The infected snakes stopped eating but just ate now and then, did not regurge and that for quite a long time, but when they got worse the poop got smelly and runny, with blood also. Not sure which antibitioc I used back then, have to look it up.

Edit; I had Doxycycline prescribed for that, an antibiotic from a different group then Baytrill. So, if it would be Chlamydophila psittaci, they might not have been killed by the Baytrill.

If nothing shows up, it might be a virus... then she has to fight it on her own with the best support you can give her.
 
A few thoughts and hypotheses.

I am by no means an expert but I think both the digestive enzyme and the low stomach acid ideas have merit. Maybe even something similar to an ulcer?

I do have a few questions. Where do you get your feeders? Has all the food she's eaten (regurgitated or not) come from the same source? What if it's something to do with the husbandry of the mice or maybe it's a food allergy to whatever is fed to the mice. Certain supplements or antibiotics? Even though you've been feeding pinkies, they still received their nutrients from whatever the mother ate. Also, it could be a cleaning product used by the "feeder breeder" that has gradually built up to toxic levels in the mice or your snake may just be hyper-sensitive to it. I would try another mouse supplier if you haven't already. I don't think there are any feeder mice raised in "free range" environments or that are "grass/grain fed" but it might be worth a shot. Maybe even another food source altogether, such as lizards or even chicken bits as has suggested by other members on this site as an alternative to mice? I don't think she has an allergy to rodents but at this point, anything's possible. Good luck and keep us updated!
 
Thanks Everyone!

I am by no means an expert but I think both the digestive enzyme and the low stomach acid ideas have merit. Maybe even something similar to an ulcer?

I do have a few questions. Where do you get your feeders? Has all the food she's eaten (regurgitated or not) come from the same source? What if it's something to do with the husbandry of the mice or maybe it's a food allergy to whatever is fed to the mice. Certain supplements or antibiotics? Even though you've been feeding pinkies, they still received their nutrients from whatever the mother ate. Also, it could be a cleaning product used by the "feeder breeder" that has gradually built up to toxic levels in the mice or your snake may just be hyper-sensitive to it. I would try another mouse supplier if you haven't already. I don't think there are any feeder mice raised in "free range" environments or that are "grass/grain fed" but it might be worth a shot. Maybe even another food source altogether, such as lizards or even chicken bits as has suggested by other members on this site as an alternative to mice? I don't think she has an allergy to rodents but at this point, anything's possible. Good luck and keep us updated!

I'm going to have to consider this. It is a possibility that she is lacking something. I have used nutribac on her, because she has been regurgitating. Hmmmmm, I am going to have to have a talk with the vet regarding this. Maybe it is a digestive or enzyme issue.

The feeders I use come from multiple sources. I either breed them myself or buy them from rodentpro. I also mix it up a bit. They could eat mice one feeding, baby rats another, gerbils and hamsters. I don't use any harsh cleaning chemicals in the tanks of the mice or snakes. I change water in all my snake tanks every day to every other day. I only feed frozen thawed or fresh killed. I also slit all the feeders.

Thanks!

Wayne
 
The gas in her stomach sounds like it might be something bacterial in her gut, She may be having a problem keeping the acid levels up and the good bacteria lvls down.
It sounds very much like a typical stomach bug with people, lots of vomiting, dehydration
I would def see about getting a tube for water feeding if she isnt able to drink often on her own and the symptoms persist.
what is her poo looking like? any color changes?

Good luck! it always sucks when you dont know what is wrong!
 
The gas in her stomach sounds like it might be something bacterial in her gut, She may be having a problem keeping the acid levels up and the good bacteria lvls down.
It sounds very much like a typical stomach bug with people, lots of vomiting, dehydration
I would def see about getting a tube for water feeding if she isnt able to drink often on her own and the symptoms persist.
what is her poo looking like? any color changes?

Good luck! it always sucks when you dont know what is wrong!

The vet said something about this too, but wouldn't the course of antibiotics have taken care of that? She has another vet appointment tomorrow. Nothing out of the ordinary came from the regurge sample that I gave them. He said that it was well on it's way as far as digestion goes.

Her poops look a little weird to me, but considering that she has been on a partial pinkie, pinkie or hopper diet for the last few months, I wouldn't imagine them being normal. A lot of urates and little in the way of solids. Not like a diarrhea, but not solid either. Smells a little fishy sometimes too.

Wayne
 
Antibiotics would clear out the bad bacteria, but they can cause problems with good bacteria too, at least in humans. That's why a lot of antibiotics can have a side effect of diarrhea and taking pro-biotic supplements can help? Maybe the vet can suggest something that could strengthen her digestive flora and enzymes?
 
hi has she been tested for salmonellosis . some strains of salmonella have been found to be gastrointestinal inhabitants in many reptiles with no harm to them but in less healthy reptiles some pathogenic strain can cause digestive disorders I have read.
 
What if you try a course of a different antibiotic? What if you try her on pinky rat pieces?
 
Salmonella infection would cause green (runny) stools I've read somewhere. I've had a probable case in the past, it was also very smelly but she was not diagnosed with it because she died.
 
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