Sorry, I wasn't very clear about the difference between the FWC license and the state sales tax license. You need the FWC license even if you sell wholesale, even just one snake per year. But I don't believe you will need the resale tax license if you just sell wholesale. Also, there may be some threshold below which you do not need the sales tax license. You would have to check on that. I doubt that everyone who has a garage sale once per year charges sales tax, but maybe they are supposed to. The best thing is to check it out with the state revenue dept.
If you produce a few here in Florida, but only sell out of state (maybe go to an out of state show, or wholesale to an out of state dealer), maybe you can sidestep the license issues, since the sales would not occur in Florida. I really don't know, and can't advise about that. FWC also has some kind of free or cheap "pet keeper" permit for herps over a certain number. But I have always gotten the sales / exhibit license, so never read up on that. But it is on the same website as the permit I linked to in the last post, if you want to read about it.
Each county and city has its own regulations as well. Here in Lee County, you have to get what used to be called an occupational license, and now is called something else (I still call it an occupational license, and it still costs the same as before - about $50 per year). If your city or county requires these licenses, they will probably also check your zoning to see if you are allowed to do whatever you want to do where you live.
I am not ever suggesting that anyone just ignore the law. I am saying that if you are only producing a clutch or two per year, it might be worthwhile to do whatever is required to keep it at a hobby level and not get involved with dealing with more different levels of government than absolutely necessary - that can really take the fun out of a hobby fast. If you are producing at that level, and if sending them out of state in a trade or wholesale deal can legally allow you to sidestep dealing with government issues, then it might be worthwhile to do so. But check everything out for yourself - I am not giving any kind of legal advice here, lol! And don't necessarily just believe what a government employee tells you, either. If you talk to 5 different employees, you may get 5 different answers! Read it in black and white for yourself.